CHAITANYA BHARATHI INSTITUTE OF TECHNOLOGY (A)
  • Biotech-Bioinformatics-VI-2020-21
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    General
    Announcements
    Slip Test 1
    Assignment 1
    Assignment 2
    Slip Test 2
    UNIT I Recordings
    1. Introduction to Bioinformatics and Need of Computers in Biotechnology Research
    2. Bioinformatics- Introduction, Scope of Bioinformatics
    3. Applications of Bioinformatics
    4. Introduction to biological databases
    5. Types of biological database - Primary Databases
    6. Types of biological database - Secondary and Composite databases; File Formats
    7. File formats for biological sequence - NCBI, EMBL, SWISSPROT, FASTA and Information retrieval from biological Databases
    UNIT II Recordings
    1. Sequence database search : FASTA
    2. Sequence database search- FASTA and BLAST; Various versions of BLAST and FASTA
    3. Amino acid substitution matrices- PAM and BLOSUM
    4. Amino acid substitution matrices- PAM and BLOSUM
    5. Sequence Alignment-Local, Global alignment
    6. Methods of pairwise sequence alignment - Dot Matrix Analysis
    7. Methods of pairwise sequence alignment - Needleman Wunch Algorithm
    8. Methods of Pairwise Sequence Alignment- Smith waterman Algorithm
    9. Pairwise sequence Alignment method - Problems
    10. Multiple Sequence Alignment methods
    11. Multiple Sequence Alignment methods
    UNIT III Recording
    1. DNA Sequencing and Genome mapping
    2. Genome Sequencing
    3. cDNA Sequencing and Genome Sequence Assembly
    4. Genome Annotation
    5. Gene Prediction
    6. Gene Prediction Methods in Microbial Genomes
    7. Gene Prediction Methods in eukaryotes and Other Gene Prediction Tools
    UNIT IV Recordings
    1. Protein Structure Basics
    2. Protein Structure Visualization
    3. Protein structure comparison
    4. Protein structure classification and Protein secondary structure prediction
    5. Protein secondary structure prediction
    6. Protein tertiary structure prediction
    7. Human Genome Project
    Protein Secondary Structure Prediction
    Protein Secondary and Tertiary Structure Prediction
    Human genome project: Goals, work scope, impact
    Practical applications and limitations of Human Genome Project
    UNIT V Recordings
    1. Understanding Evolutionary process, Origin of Molecular Phylogenetics, Relationship of Phylogenetic Analysis to sequence alignment, Concept of evolutionary trees
    2. Phylogenetic Methods
    3. Tree Evaluation, Problems in Phylogenetic Analysis, Automated Tools for Phylogenetic Analysis
    BI Notes
    BI UNIT 1
    1. Introduction, scope and applications of Bioinformatics
    2. Elementary commands and protocols
    3. Introduction to biological databases, types, file formats
    4. Information retrieval from biological databases
    5. FASTA and BLAST
    6. PAM and BLOSUM
    7. Sequence alignment - local and global
    8. Pairwise sequence alignment
    9. Multiple Sequence Alignment
    10. Genome Sequencing
    11. Gene prediction
    12. Protein structure Basics
    13. Protein Structure Prediction
    14. Human Genome Project
    15. Phylogenetic analysis
    16. Human Genome Project 2file
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    Biotech-Bioinformatics-VI-2020-21
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    3. Biotechnology
    4. AY 2020-21
    5. VI Semester
    6. Biotech-Bioinformatics-VI-2020-21
    7. Summary

    Biotech-Bioinformatics-VI-2020-21

    • Teacher: Dr.V.Aruna Assistant Professor
    Skill Level: Beginner

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